Molecular Characterization and Genetic Diversity of Haplogroup E Human Lice in Guinea, West Africa

Pediculus humanus capitis, the head louse, is an obligate blood-sucking ectoparasite that occurs in six divergent mitochondrial clades (A, D, B, F, C and E). Several studies reported presence of different pathogenic agents lice specimens collected worldwide. These findings suggest louse could be a dangerous vector serious public health problem. Herein, we aimed to study genetic diversity, PHUM540560 gene polymorphisms profile Guinea, as well screen for their associated pathogens. In 2018, total 155 were from 49 individuals at Medicals Centers rural (Maférinyah village) urban (Kindia city) areas, Guinea. Specimens subjected analysis pathogens screening using molecular tools. Results showed all belonged eight haplotypes E haplogroup, with newly identified first time. The our clade E-head revealed 82.5% exhibited same polymorphism previously A-body lice. Screening targeted Acinetobacter spp., while sequencing highlighted several species, including baumannii, nosocomialis, variabilis, towneri time haemolyticus. Our report existence Guinean haplogroup E, species